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Life Sciences

Systems biology models with an engineer's toolchain

Simulate SBML Level 2 and 3 reaction networks, run parameter sweeps and Monte Carlo studies, and project models to Modelica for multi-scale analysis.

msx — life-sciences
$ msx lint ./models --format json
$ msx mc Pathway pathway.mo
$ msx surrogate Pathway pathway.mo
The challenge

What slows life sciences teams down

01

Reproducibility

Published models are hard to re-run exactly as described.

02

Uncertain parameters

Kinetic parameters are uncertain, so single runs aren't enough.

03

Siloed knowledge

Ontologies and models are rarely connected in a queryable way.

Reference workflow

One pipeline, end to end

  1. 1

    Import

    SBML L2 / L3

  2. 2

    Annotate

    OWL2 ontologies

  3. 3

    Simulate

    ODE kinetics

  4. 4

    Analyze

    Monte Carlo & surrogates

Capabilities

What ModelScript does for you

Reaction kinetics

Streaming SBML parsing and ODE simulation of reaction networks.

Uncertainty

Monte Carlo and surrogate models for parameter studies.

Ontology links

Connect models to OWL2 ontologies with SPARQL queries.

Multi-scale

Project biochemical networks into Modelica.

Open-core toolchain that runs anywhere

Browser, CLI, VS Code, CI pipelines, or air-gapped Enterprise Appliances (AGPL-3.0 Core & Commercial Editions).

Open-Core under the GNU AGPL v3 License; Enterprise Edition (ee/) under the ModelScript Enterprise License. • Trademark Policy